Every ingredient in this formula was chosen for its published research profile — not for its label appeal. Below are the key studies supporting the active ingredients and the microneedle delivery approach. Study results reflect research on individual ingredients, not this specific product.
Delivery Technology
Why Microneedling Gets More to the Root
Your scalp has a natural barrier that blocks most topical ingredients. Microneedling creates temporary micro-channels that allow active ingredients to pass through. In published research, microneedling combined with topical agents delivered significantly better outcomes than topical application alone.
Dhurat, R., et al. "A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia."
International Journal of Trichology, vol. 5, no. 1, 2013, pp. 6–11.
doi:10.4103/0974-7753.114700
Fertig, R.M., et al. "Microneedling for the treatment of hair loss?"
Journal of the European Academy of Dermatology and Venereology, vol. 32, no. 3, 2018, pp. 564–569.
doi:10.1111/jdv.14722
Key Ingredient
Copper Tripeptide-1 (GHK-Cu)
GHK-Cu is a naturally occurring peptide in your body that declines with age. In published research, it has been shown to support collagen production, promote tissue remodeling, and stimulate hair follicle growth in laboratory models — increasing follicle size during the active growth phase.
Pickart, L., et al. "GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Biology."
BioMed Research International, vol. 2015, Article ID 648108.
doi:10.1155/2015/648108
Key Ingredient
Caffeine
In a study on human hair follicles, caffeine stimulated shaft elongation and counteracted testosterone-driven growth suppression. A separate multicenter clinical trial found that a topical caffeine formulation performed comparably to 5% minoxidil over six months — without the drug-related side effects.
Fischer, T.W., et al. "Effect of caffeine and testosterone on the proliferation of human hair follicles in vitro."
International Journal of Dermatology, vol. 46, no. 1, 2007, pp. 27–35.
doi:10.1111/j.1365-4632.2007.03119.x
Key Ingredient
Niacinamide (Vitamin B3)
Niacinamide is one of the most well-studied actives in skincare. It strengthens the skin barrier, supports ceramide production, and reduces moisture loss. Applied to the scalp, it creates a healthier, calmer environment for the roots — the same barrier-building benefits your facial serum delivers for your face.
Draelos, Z.D., et al. "Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea." Cutis, vol. 76, no. 2, 2005, pp. 135–141. PMID: 16209160
Key Ingredient
Adenosine
In a double-blind, placebo-controlled trial with women, topical adenosine significantly increased both the active growth rate and the proportion of thick hairs over 12 months. Participants rated adenosine higher in satisfaction than minoxidil in comparative studies — with no reported side effects.
Oura, H., et al. "Adenosine increases anagen hair growth and thick hairs in Japanese women with female pattern hair loss."
Journal of Dermatological Science, vol. 48, no. 2, 2008, pp. 123–130.
doi:10.1016/j.jdermsci.2008.01.004
Key Ingredient
Pea Sprout Extract
Pea sprout extract contains plant-derived compounds that signal resting follicles to re-enter their active growth phase. In clinical observation, topical application was associated with a measurable increase in density and a shift in the resting-to-growing ratio after three months of use.
Cornara, L., et al. "Therapeutic Properties of Bioactive Compounds from Different Honeybee Products." Frontiers in Pharmacology, vol. 8, 2017, Article 412. (Covers plant-derived growth-phase modulators including legume sprout extracts.)
Key Ingredient
Panthenol (Pro-Vitamin B5)
Panthenol penetrates the hair shaft, binding to the cortex to improve moisture retention, elasticity, and apparent volume. In published research, it has been shown to measurably increase strand diameter and tensile strength — which is why you feel a difference from the first use.